Subchondral bone marrow lesion

Subchondral bone marrow lesions (BMLs) are pathological changes found within the bone marrow just beneath the cartilage of a joint.

These lesions are typically identified as areas of increased fluid in the bone marrow, visible on magnetic resonance imaging (MRI) scans.

BMLs are often associated with joint pain and are considered a hallmark of osteoarthritis, though they may also arise due to acute injury or stress to the bone.

These lesions affect the bony organ system and are located specifically in the musculoskeletal region, commonly affecting joints such as the knees, hips, or shoulders.

The presence of BMLs is indicative of underlying bone stress or microfractures, as well as inflammation.

The bone marrow's response to such stress includes increased vascularity and edema, which can contribute to pain and may lead to further joint degeneration if not addressed.

Clinically, subchondral BMLs are significant because they can be predictive of the progression of osteoarthritis.

They are often associated with cartilage loss and joint space narrowing.

Treatment strategies may include addressing pain and inflammation, modifying activities to reduce stress on the joint, and sometimes surgical intervention.

Detection of subchondral bone marrow lesions is primarily achieved through MRI as it provides detailed imaging of soft tissues, including bone marrow.

The condition is a focal point in the management of joint diseases, highlighting the importance of early detection and intervention to prevent further joint damage.