Polymyositis is an inflammatory muscle disease characterized by muscle weakness and inflammation.
It predominantly affects the skeletal muscles, which are the muscles that are under voluntary control and are involved in body movement.
This condition is part of a group of diseases known as inflammatory myopathies and is considered an autoimmune disorder.
In polymyositis, the body's immune system mistakenly attacks its own muscle fibers, leading to muscle inflammation and weakness.
Muscle weakness in polymyositis often begins in the muscles closest to the trunk of the body, such as the neck, shoulder, and hip muscles.
Patients may experience difficulty climbing stairs, lifting objects, or even rising from a seated position.
Over time, if untreated, the affected muscles may undergo atrophy, leading to decreased muscle bulk and further weakness.
Diagnosis of polymyositis typically involves a combination of clinical evaluation, laboratory tests such as elevated muscle enzymes, electromyography, and sometimes muscle biopsy.
Imaging techniques, specifically MRI, can be used to detect inflammation in muscles and are useful in guiding diagnosis and treatment.
Treatment for polymyositis focuses on reducing inflammation and suppressing the immune response.
This often involves the use of corticosteroids and other immunosuppressive medications.
Physical therapy is also a crucial component of treatment, aimed at maintaining muscle strength and function.