Paraganglioma

Organ
Lymphatic
Region
Neck

Detectable on Scans

Head & TorsoWhole Body

About this Condition

Paraganglioma is a rare type of tumor that arises from the paraganglia, a collection of nerve cells that are part of the autonomic nervous system.

These tumors are typically found in the head and neck region, although they can also occur in the abdomen or chest.

Paragangliomas in the neck are often located near the carotid artery or within the vagus nerve pathway.

This condition can affect the body by causing symptoms associated with nerve compression and hormone secretion, as some paragangliomas can produce catecholamines, leading to symptoms similar to those of a pheochromocytoma, such as high blood pressure, palpitations, and headaches.

The exact cause of paragangliomas is not completely understood, but genetic factors play a significant role, with several familial syndromes associated with these tumors.

Diagnosis typically involves imaging studies such as CT or MRI scans, which can help locate the tumor and assess its extent.

Functional imaging, such as PET scans, may also be employed to evaluate metabolic activity.

Treatment often involves surgical resection, and in some cases, radiation therapy may be necessary.

Due to the potential for malignancy and metastatic spread, regular follow-up is crucial for managing this condition.