Pancreatic agenesis

Pancreatic agenesis is a rare congenital condition characterized by the complete absence of the pancreas.

This organ, located in the abdomen, plays a critical role in digestion and blood sugar regulation.

The pancreas produces enzymes essential for digesting food and hormones such as insulin, which regulates blood glucose levels.

Without a pancreas, individuals are unable to properly digest food or regulate blood sugar, leading to severe diabetes mellitus and malabsorption issues.

This condition is typically identified through imaging scans such as an ultrasound or MRI of the abdomen, often prompted by clinical symptoms of severe diabetes in newborns or infants.

Genetic testing may also be employed to confirm the diagnosis and identify any associated syndromes or genetic mutations.

Pancreatic agenesis requires lifelong management, including enzyme replacement therapy to aid digestion and insulin therapy for diabetes management.

Multidisciplinary care involving endocrinologists, gastroenterologists, and dietitians is essential to address the complex needs of affected individuals.

Early detection and comprehensive treatment are crucial for improving quality of life and preventing complications associated with this condition.