Kimura disease

Kimura disease is a rare, chronic inflammatory disorder primarily affecting the lymphatic system.

It is characterized by painless subcutaneous nodules and swollen lymph nodes, predominantly in the head and neck region.

This condition is more commonly seen in young Asian males, although its etiology remains unclear.

Histologically, Kimura disease is marked by lymphoid follicular hyperplasia, eosinophilic infiltration, and proliferation of blood vessels.

Patients may also experience elevated serum IgE levels and peripheral eosinophilia.

Clinically, the disease manifests as soft-tissue swellings that are often mistaken for other conditions such as lymphomas or salivary gland tumors.

Diagnosis is typically achieved through a combination of clinical evaluation, imaging studies, and confirmatory biopsy.

Imaging techniques such as ultrasound, CT, and MRI can reveal the extent of lymph node involvement and surrounding tissue changes.

Treatment options vary depending on the severity and may include surgical excision, corticosteroids, or immunosuppressive therapy.

Despite its benign nature, Kimura disease can recur, necessitating long-term monitoring.

Understanding and recognition of this condition are crucial for accurate diagnosis and appropriate management.